Epithalon (also spelled epitalon) is a pineal-gland tetrapeptide studied for telomerase activity, sleep, and circadian rhythm, and popular in longevity protocols. Human evidence is early-stage. Ivologist prescribes it in cycles after a medical telehealth consultation. Epithalon is not FDA-approved.
Epithalon
A clinician-guided Epithalon protocol for individuals exploring longevity and sleep support, prescribed in 12-week cycles. Includes provider consultation, medication supply, and care guidance.
You save $99
- Clinician consultation
- Peptide medication
- Free shipping
- May require labs
One-time payment, not a subscription. Up to 3 cycles per year. A cycle is the program length; your provider decides whether treatment is right for you and sets your dose, schedule and duration. We do not offer clinical trials. Individual results may vary.
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Epithalon is researched for its potential influence on telomerase activity, the enzyme that maintains telomeres.
Modeled on a pineal-gland peptide, it's studied for melatonin and circadian regulation. Human evidence is early-stage.
Licensed providers determine dosing, frequency, and duration based on medical history and clinical evaluation.
Prescribed in 12-week cycles with breaks between them rather than continuous use.
When clinically appropriate, may be coordinated alongside longevity, sleep, or aesthetic programs.
All treatment plans require medical evaluation and approval. Individual results may vary.
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Personalized Intake
Tell us about your health, goals, and history through a secure intake questionnaire.
Clinician Review
A licensed clinician reviews your information and determines what's right for you.
Diagnostic Lab Testing
Baseline lab work checks your health markers before any peptide is prescribed.
Clinical Evaluation
A provider reviews your labs with you in a live video visit and confirms your suitability for peptide therapy.
Medication Delivered
Your prescribed medication is prepared by a partner pharmacy and shipped to your home.
Ongoing Support
Your progress is monitored with follow-ups and adjustments as needed.
Built around 12-week cycles
Peptide programs are sold in 12-week cycles (about 3 months). You can buy one cycle or a bundle of up to 3 cycles up front, with a maximum of 3 cycles per year.
Labs and a provider consultation are required.
Every peptide program starts with lab work and a live consultation with a licensed provider before anything is prescribed.
- Lab panel includedOne cycle at a time
- Bundle of 2 · save 7.5%
- Bundle of 3 · save 12.5%
- Clinician consultation & follow-up access
- All peptide medication for the cycle
- Shipping to your door
- Injection supplies & dosing guide
Peptide therapy
Not sure which peptide program is right for you?
Talk it through first in a free 15-minute provider consultation. A U.S.-licensed provider will go over your goals and health history, explain how the programs work, and help you decide whether one is right for you before you commit to a cycle. There is no obligation to start treatment.
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Understanding Cellular Aging and Circadian Rhythm
Cellular resilience and sleep rhythms shift with age. Learn how clinician-guided Epithalon therapy may support telomerase activity, sleep quality, and circadian balance.
Understanding Cellular Aging & Circadian Rhythm
Learn about Epithalon, how it works, and how clinician-guided therapy may support your longevity and sleep goals.
The Physiology
Proposed Pineal Peptide Signaling
Pineal peptide → Telomerase + melatonin/circadian signaling
Epithalon is modeled on a substance produced by the pineal gland and is studied for supporting telomerase activity and regulating melatonin and circadian rhythm, alongside antioxidant activity. Human evidence is early-stage.
With age, these systems shift, which may affect sleep and cellular resilience.
Symptoms
Symptoms & Signals
Some individuals report patterns such as:
Experiencing multiple patterns may warrant clinician evaluation.
Who Is It For?
Who May Benefit from Epithalon?
Epithalon may be considered for adults who are:
Clinical evaluation is required. Your eligibility will be determined by a licensed provider.
Epithalon vs Melatonin
Epithalon vs Melatonin
How the two differ. Epithalon's human evidence is early-stage.
Epithalon
A peptide studied for supporting the body's own circadian and telomerase-related pathways.
- Cyclical dosing
- Researched for cellular-aging markers
- Studied for effects upstream of sleep signaling
Melatonin
A hormone taken directly to signal sleep timing.
- •Direct supplementation
- •Targets sleep onset
- •Not used for cellular-aging pathways
Treatment decisions are determined through clinician evaluation.
Protocol
Protocol Philosophy
Epithalon is prescribed in 12-week cycles.
An example, not your plan. This page offers injectable Epithalon only. The 12-week cycle you choose is the program: clinician consultation, peptide medication and free shipping; labs may be required. It is not a dosing schedule; your provider decides your dose, how often and for how long.
Cycle (12 Weeks)
Dosing runs through the cycle on the schedule your clinician sets.
Between Cycles
A break between cycles rather than continuous use.
Repeat (Up to 3 Cycles a Year)
Your clinician reviews your response before another cycle.
Ongoing
Any longer-term use is your provider's decision, reviewed cycle by cycle.
Responses vary by individual.
Research Findings and Limits
Research Findings and Limits
What Epithalon has been studied for, and the kind of study behind each:
Limits of the research. Epithalon's human evidence is early-stage and long-term human data is limited. No outcome is guaranteed.
Individual responses vary.
Designed for Safety. Guided by Clinicians.
- Early-stage evidence — Epithalon is compounded, not FDA-approved, and its human data is limited, which your provider weighs with you
- Gradual, not instant — sleep-wake and longevity support are assessed over a full 12-week cycle, not in days
- Generally very well tolerated — mild injection-site reactions are the most commonly reported effect
Epithalon is screened for contraindications (active or recent cancer, pregnancy and breastfeeding) before it is prescribed
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Legitscript certifiedIndividual experiences vary. Testimonials reflect personal opinions and do not guarantee outcomes.
The licensed providers behind your personalized care
Dr. Utkal Patel
MD, Internal Medicine
Critical Care Medicine
Samantha Alonso
Board Certified
Family Nurse Practitioner
Dalila Tarr
FNP-BC
Nurse Practitioner
Dr. Randa Soukieh
Board Certified
Family Medicine
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Board Certified
Internal Medicine, Nephrology and Critical Care
Carrie Ferguson
FNP, BC
Nurse Practitioner
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AGACNP-BC
Nurse Practitioner
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FNP
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FNP-BC, BSN, RN
Nurse Practitioner
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FNP-C, AGACNP-BC
Nurse Practitioner
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Board Certified
Internal Medicine
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MD, FCCP
Internal Medicine, Pulmonary & Critical Care
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MSN, RN, APRN, FNP-BC
Nurse Practitioner
Brandon Olinger
AGACNP-BC
Nurse Practitioner
Brenda Ballard
Integrative Health Practitioner
Health Coaching
Lauren Grube
Integrative Health Practitioner
Health Coaching
Frequently Asked Questions
Get answers to commonly asked questions.
Epithalon (epitalon) is a synthetic four-amino-acid peptide modeled on a pineal-gland substance. It is studied as a longevity and circadian-regulation peptide and is available as a compounded prescription medication.
It is studied for cellular-aging markers, sleep quality, and circadian rhythm. Human evidence is early-stage, so it is used as a supervised longevity tool rather than a proven treatment.
No. Epithalon is not FDA-approved. It is compounded by licensed 503A pharmacies and prescribed individually after a medical evaluation.
Research suggests epithalon may influence telomerase, the enzyme that maintains telomeres, and help regulate melatonin and circadian signaling, with antioxidant activity. Much of the human data is early-stage.
It is a subcutaneous injection prescribed in 12-week cycles, with up to three cycles a year. Your provider sets the exact dosing schedule within each cycle.
Still have questions? Contact us